Interdisciplinary Biological Services Research Centre

At the Swenam Canadian Institute of Research & Innovation (SCIRI), the Interdisciplinary Biological Services Research Centre is dedicated to advancing knowledge and innovation in various fields within the life sciences. Our research clusters focus on biotechnology, genomics, biomedicine, environmental science, and sustainability, recognizing these as key areas for future exploration, discovery, and educational advancement.

Equipped with state-of-the-art high-throughput experimentation facilities, our center empowers researchers to delve into the intricate interplay among the genome, proteome, and metabolome, unraveling biological processes at unparalleled rates and scales.

We offer a comprehensive suite of services, including:

  • Custom assay design and protocol development
  • In-Vitro Biology
  • Drug Metabolism and Pharmacokinetics (DMPK)
  • Non-GLP Bioanalysis
  • In-Vivo Pharmacology Studies
  • Pharmaceutical Microbiology Testing
  • Toxicology
  • Development of primary cell cultures encompassing mammalian, insect, plant, fungal, and bacterial cell cultures
  • Cell-based assays for diverse applications
  • Quantification of gene expression in prokaryotic and eukaryotic cells using RT PCR
  • Quantification of gene copies in environmental samples via rt-PCR
  • DNA/RNA quantification using Pico Green/Ribo Green assay
  • High-throughput screening
  • Identification of bacteria and fungi through 16S, 18S, 25S rDNA analysis
  • Preparation of amplifiable DNA from samples contaminated with heavy metals
  • Immunocytochemistry
  • Gene cloning
  • Enzymatic assays
  • Electrophoresis
  • Antibiotic assays, including Minimum Inhibitory Concentration (MIC), Disk Diffusion Method, Dilution Method, and Quantitative antimicrobial test for textiles and solid materials
  • Microscopy and image analysis
  • Cryopreservation and cell banking services
  • Custom lyophilization (freeze drying) services for small and bulk samples
  • Folate status assessment
  • Vitamin B12 status assessment via Dried blood spot (DBS) methylmalonic acid (MMA) in plasma or serum
  • Vitamin B6 status assessment using LC-MS/MS platform for Pyridoxal 5′-phosphate, Cystathionine, Total homocysteine, and Kynurenine metabolites
  • Vitamin B2 (riboflavin) status assessment through LC-MS/MS platform for Riboflavin, Flavin adenine dinucleotide (FAD), and Flavin mononucleotide (FMN)
  • Vitamin D status assessment and circulating forms using LC-MS/MS platform for 25-hydroxy-vitamin D2, 25-hydroxy-vitamin D3, 1,25-dihydroxy-vitamin D2, 1,25-dihydroxy-vitamin D3, and 3-epi-25-hydroxy-vitamin D3
  • Biomarkers of one-carbon metabolism and related metabolites analyzed via LC-MS/MS or HPLC, including Choline, Dimethylglycine, Betaine, Methionine, Homocysteine, Cystathionine, Cysteine, Taurine, Glycine, Serine, Cysteinylglycine, and Glutathione.

Our center is committed to facilitating cutting-edge research and providing tailored solutions to meet the diverse needs of the scientific community and industry partners. For cost estimates or fee-for-service analyses, please contact us by email at [email protected]